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Research done at Ohio State University College of Medicine showed that oral MSM can protect rats against the onset of breast cancer. Rats bred to be susceptible to breast cancer when given certain carcinogenic compounds were fed a diet containing added MSM for eight days. Following this period the rats were given 15 mg doses of 7,12-dimethylbenzanthracene by oral gastric intubation. The health of the rats was monitored for nearly one year and compared to a similar group of carcinogen-dosed rats that had not received the MSM diet. Although there was no statistical difference in the number of tumors developing in the two groups, the MSM diet rats developed their first tumors 100 days later than the non-MSM diet rats, and these tumors became cancerous about 130 days later than those in the control group.

The same researchers from the Ohio State University College of Medicine also studied the protection that dietary MSM provided rats injected with 1,2-dimethylhydrazine, a compound that induces colon cancer. One group of rats received MSM as a 1% solution in their drinking water during the experiment. The control group received only tap water. One week after the start of the dietary regimen, all rats were injected with the carcinogen. At two-month intervals the rats were examined under anesthesia for tumors. Rats without any appearance of tumors were returned to the experiment. Again, the number of bowel tumors occurring in the rats was statistically the same for treated and untreated rats over the entire nine-month experiment. However, the time of appearance of the first bowel tumors was considerably longer in the MSM treated rats. The conclusion of the researchers was that MSM significantly lengthens the time of tumor onset compared to controls and MSM should be further investigated as a preventive for colon cancer.

Researchers at Oregon Health Sciences University studied a strain of mice that were prone to spontaneous development of joint lesions similar to those in rheumatoid arthritis. They found that animals fed a diet that included a 3% solution of MSM, in drinking water from the age of two months until the age of five months, suffered no degeneration of articular cartilage. In the control group of mice receiving only tap water, 50% of the animals were found to have focal degeneration of articular cartilage.

Finally, recent human research at the UCLA School of Medicine found an 82% reduction in pain after six weeks of oral MSM use in a double blind study on degenerative arthritis. The study spanned four months and involved sixteen patients: ten patients on MSM and six on placebo. After only six weeks, those patients using the MSM experienced better than 80% control of their pain, while those on the placebo experienced on average an 18% improvement at six weeks.

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References

  • Crown-Zellerbach Corp., Toxicity bulletin 1983.

     

  • Herschler, R. J., U.S. Patent No. 4,973,605, Nov. 27, 1990.

     

  • Istituto di Ricerche Biomediche, RBM EXP., No. 980174, Aug. 19, 1998.

     

  • Jacob, J.W. and Herschler, R., Ann. N.Y. Acad. Sci., Vol. 411, xiii, 1983.

     

  • Jacob, S.W., Oregon Health Sciences University, Portland, Oregon, personal communication.

     

  • Lawrence, R. M., U.C.L.A. School of Medicine, Methyl-Sulfonyl-Methane, A Preliminary Correspondence.

     

  • Lovelock, J.E. et al., Nature, Vol. 237, 452, 1972.

     

  • McCabe, D. et al., Arch. Surg., Vol. 121, 1455, 1986.

     

  • Morton, J. I. & Moore, R. D., Federation of American Societies for Experimental Biology, 69th Annual Meeting, April 21-26, 1985, 692, 1985.

     

  • O'Dwyer, P.J. et al., Cancer, Vol. 62, 944, 1988.

     

  • Richmond, V. L., J. Nutrition, Vol. 116, No. 6, June 1986.

     

  • Williams, K.I.H. et al., Arch. Biochem. Biophys., Vol. 113, 251, 1966.

     

  • Williams, K.I.H. et al., Proc. Exp. Biol. & Med., Vol. 122, 865, 1966.

 

 

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